We develop cutting-edge bioanalytical tools combining materials chemistry, bioimaging, microfluidics, and AI driven analytics to reveal innerworkings of biological complexity. Using the newly developed technologies, we unveil the molecular and cellular mechanisms driving the ensemble behavior of native biological systems. The specific systems and biological questions we ask constantly evolve but we are generally interested in brains, tumor tissues, and microbial communities, the systems that have inherent heterogeneity and strong intercellular interactions. Our research projects range from technology development to discovery of new biology. Below we characterize our research projects into two main technologies that we leverage: microfluidcs and spatial transcriptomics