Book Chapters

Double Emulsion Flow Cytometry for Rapid Single Genome Detection

Cowell, T.W.; Han, H.-S.*

In: Li, P.C., Wu, A.R. (eds), Single-Cell Assays. Methods in Molecular Biology, Vol. 2689. Humana, New York, NY 2023. article

Pending Publications

MilliMap: interactive closed-loop analysis for spatial omics

Feng, Q.; Qian, S.B.; Wan, J.; Starr, Z.R.; Asif, S.; Han, H.-S.*

Submitted. article

Social evolution and absence of olfactory function in larval honey bees

Peng, T.; Chen, Z.; Ahmed, A.C.; Feng, Q.; Yeo, S.; Han, H.-S.; Robinson, G.E.*

Submitted. article

SpaceExpress: a method for comparative spatial transcriptomics based on intrinsic coordinate systems of tissues

Kim, Y. J.; Ojha, A.; Schrader, A..; Lee, J.; Wu, Z.; Traniello, I. M.; Robinson, G. E.*Han, H.-S.*; Zhao, S. D.*; Sinha, S.*

Submitted. article

Unbiased, Cell-free Profiling of Single Influenza Genomes at High-throughput

Cowell, T. W.; Puryear, W.; Chen, C.-L.; Ding, R; Runstadler, J.; Han, H.-S.*

Submitted. article

Publications

RESCUE: recovery of unattributed expression patterns in spatial transcriptomics

Lee, Y.J.; Yeo, S.; Schrader, A.W.; Lee, J.; Traniello, I.M.; Asadian, M.; Ahmed, A.C.; Robinson, G.E.; Han, H.-S*.; Zhao, S.D*.

Nature Communications2026article

Systematic investigation of double emulsion dewetting dynamics for the robust production of giant unilamellar vesicles

Jing, W.; Noh, H.; Tan, J.C.; Wu, N.C.; Han, H.-S.*

Lab on a Chip2026article

Seq-Scope-eXpanded: spatial omics beyond optical resolution

Anacleto, A.; Cheng, W.; Feng, Q.; Park, A.; Cho, C.-S.; Hwang, Y.; Kim, Y.; Si, Y.; Hsu, J.-E.; Zhao, Q.; Zhao, X.; Kim, D.; Schrank, M.; Schrader, A.W.; Yeo, S.; Teles, R.; Modlin, R.L.; Plazyo, O.; Gudjonsson, J.E.; Kim, M.; Kim, C.H.; Han, H.-S.*; Kang, H.M.*; Lee, J.H.*

Nature Communications2026, 17, 2564. article

Shear-Induced CROSS (Cellular RedOx Spreading Shield) Assembly Sustains Neurotrophic Extracellular Vesicle Production for Functional Neural Networks

Miller, R. C.; Kang, S.; Wang, J.; Huang, K.-Y.; Lee, J.; Kim, Y. J.; Han, H.-S.*; Kong, H.*

Advanced Functional Materials2025, 36(27), e22252. article

Single-step synthesis of mesoporous vinyl polymers via hierarchical assembly of stereocontrolled chains

Kim, S. H.; Jo J.; Park, T. W.; Chung, Y. M.; Song, H. H.; Lee, S. W.; Park, Y.; Moon, W. K.; Lee, E.J; Hwang, G. W.; Jung, M. H.; Hong, W. K.; Sohn ,D.; Lee, Y.; Yoon, K. B.; Shin, S. H.; Han, H.-S.*; Han, Y. K.*

Small2025, 21(51), e09954. article

Drop-by-drop Addition of Reagents to a Double Emulsion

Cowell, T. W.; Jing W.; Noh, H.; Han H.-S.*

Small2024, 20(46), e2404121. article

Targeted whole-genome recovery of single viral species in a complex environmental sample

Chen, L.; Chen, A.; Zhang, X. D.; T. Robles, M. S.; Han, H.-S.; Xiao, Y. Xiao, G.; Pipas, J. M.; Weitz, D. A.;

PNAS2024, 121(31), e2404727121. article

Organoborane Se and Te precursors for controlled modulation of reactivity in nanomaterial synthesis

Park, J.; Han, H.-S.

ACS Nano2024, 18, 24, 15487–15498. article

Intracellular Spatial Transcriptomic Analysis Toolkit (InSTAnT)

Kumar, A.; Schrader, A. W.; Boroojeny, A. E.; Asadian, A.; Lee, J.; Song, Y. J.; Zhao, S. D.*; Han, H.-S.*; Sinha, S.* 

Nature Communication, 2024, 15, 7794. article

Spot-Based Global Registration for Sub-pixel Stitching of Single-Molecule Resolution Images for Tissue-Scale Spatial Transcriptomics

Yeo, S.; Schrader, A. W.; Lee, J.; Asadian, A.; Han, H.-S.*

Analytical Chemistry2024, 96(17),  6517-6522. article

Versatile Pre-Polymer Platform for Controlled Tailoring of Quantum Dot Surface Properties

Lee, J.; Soares, G.; Doty, C.; Park, J.; Hovey, J.; Schrader, A. W.; Han, H.-S.*

ACS Appl. Mater. Interfaces, 2024, 16, 12, 15202-15214 .article

Multiplexed Electrical Detection of Whole Viruses from Plasma in a Microfluidic Platform

Jankelow, A.; Chen, C.; Cowell, T. W.; Monteros, J. E.; Bian, Z.; Kindratenko, V.; Han H.-S.; Valera, E.; Bashir, R.

Analyst2024, Advance online publication. article

Spectroscopic Investigation of Phosphorus Mineralization as Affected by the Calcite-Water Interfacial Chemistry

Chen, A.; Zhu, L.; Han H.-S.; Arai, Y.

Environ. Sci. Technol. 202357(43), 16606–16615. article

Electrochemical Point-of-Care Devices for the Diagnosis of Sepsis

Valera, E.; Kindratenko, V.; Jankelow, A.; Heredia, J.; Cowell, T. W.; Chen, C.-L.; Han, H.-S.; Bashir, R.*

Curr. Opin. Electrochem202339, 101300. article

In-drop thermal cycling of microcrystal assembly for senescence control (MASC) with minimal variation in efficacy

Miller, R. C.; Lee, J.; Kim, Y.; Han, H.-S.*; Kong, H.* 

Adv. Funct. Mater202333(37), 2302232. article

Extending the bioavailability of hydrophilic antioxidants for metal ion detoxification via recrystallization with polysaccharide dopamine

Miller, R.; Kim, Y.; Park, C. G.; Torres, C.; Kim, B.; Lee, J.; Flaherty, D.; Han, H.-S.; Kim, Y. J.*; Kong, H.*

ACS Appl. Mater. Interfaces2022, 14, 35, 39759–39774. article

Multiphoton phosphorescence quenching microscopy reveals kinetics of tumor oxygenation during anti-angiogenesis and angiotensin signaling inhibition

Martin, J.; Lanning, R.; Chauhan, V.; Martin, M.; Mousa, A.; Kamoun, W.; Han, H.-S.; Lee, H.; Stylianopoulos, T.; Bawendi, M.; Duda, D.; Brown, E.; Padera, T.; Fukumura, D.; Jain, R. 

Clinical Cancer Research2022, 28, 14, 3076-3090. article

Droplet Microfluidics for High-Resolution Virology

Jing, W.; Han, H.-S.*

Anal. Chem. (invited Perspective)2022, 94, 23, 8085–8100. article

Simplified, Shear Induced Generation of Double Emulsions for Robust Compartmentalization during Single Genome Analysis

Cowell, T. W.; Dobria, A.; Han, H.-S.*

Biorxiv 2021/469484. ACS Appl. Mater. Interfaces2022, 14, 18, 20528–20537. article

Inertial Self-Assembly Dynamics of Interacting Droplet Ensembles in Microfluidic Flows

Jing, W.; Han, H.-S.*

Analytical Chemistry2022, 94, 9, 3978-3986. article

Nanocrystal Precursor Incorporating Separated Reaction Mechanisms for Nucleation and Growth to Unleash the Potential of Heat-up Synthesis

Park, J.; Jayaraman, A. R.; Wang, X.; Zhao, J.; Han, H.-S.*

ACS Nano, 2020, 14, 9, 11579-11593. article

Controllable modulation of precursor reactivity using chemical additives for systematic synthesis of high-quality quantum dots

Park, J.; Jayaraman, A. R.; Schrader, A. W.;  Hwang, G. W.; Han, H.-S.*

Nature Comm, 2020, 11, 5748. article (selected as Editor’s highlightfeatured article in Materials Science and Chemistry)

Rapid, Multiplexed Electrical Detection of Biomolecules using Electrically Distinct Hydrogel Beads

Cowell, T. W.; Valera, E.; Jankelow, A.; Park, J.; Schrader, A. W.; Ding, R.; Berger, J; Bashir, R.; Han, H.-S.*

Lab Chip. 2020, 20, 2274-2283. article (selected as the inside front cover article)

Whole-Genome Sequencing of a Single Viral Species from a Highly Heterogeneous Sample

Han H.-S.; Cantalupo P. G.; Rotem A.; Cockrell S. K.; Carbonnaux M.; Pipas J. M.; Weitz D. A.

Chem. Int. Ed2015, 54, 13985–13988. article 
* Above article was selected as a “Hot paper”.

Quantum Dot/Antibody Conjugates for In vivo Cytometric Imaging in Mice

Han H.-S.; Niemeyer E.; Huang Y.; Kamoun W. S.; Martin J. D.; Bhaumik J.; Chen Y.; Roberge S.; Cui J.; Martin M. R.; Fukumura D.; Jain R. K.; Bawendi M. G.; Duda D. G. 

Proc. Natl. Acad. Sci. U.S.A. 2015, 112, 1350–1355. article

Compact High-Quality CdSe-CdS Core-Shell Nanocrystals with Narrow Emission Linewidths and Suppressed blinking

Chen O.; Zhao J; Chauhan V. P.; Cui J.; Wong C.; Harris D. K.; Wei H.; Han H.-S.; Fukumura D.; Jain R. K.; Bawendi M. G. 

Nat. Mater. 2013, 12, 445–451. article

Controlled Placement of Colloidal Quantum Dots in sub-15-nm Clusters

Manfrinato V. R.; Wanger D.D.; Strasfeld D. B.; Han H.-S.; Marsili F.; Arrieta J. P.;Mentzel T. S.; Bawendi M. G.; Berggren K. K.

Nanotechnology2013, 24, 125302. article

Spatial Charge Configuration Regulates Nanoparticle Transport and Binding Behavior in vivo

Han H.-S.; Martin J.; Lee J.; Harris D. K.; Fukumura D.; Jain R. K.; Bawendi M. G.

Angew. Chem. Int. Ed. 2013, 52, 1414–1419. article
* Above article was highlighted in Nat. Mater. 2013, 12, 91.

Compact Zwitterion-Coated Iron Oxide Nanoparticles for Biological Applications

Wei H.; Insin N.; Lee J.; Han H.-S.; Cordero J. M.; Liu W.; Bawendi M. G.

Nano Lett2012, 12, 22–25. article

Synthesis of Cadmium Arsenide Quantum Dots Luminescent in the Infrared

Harris D. K.; Allen P. M.; Han H.-S.; Walker B. J.; Lee J.; Bawendi M. G.

J. Am. Chem. Soc. 2011, 133, 4676–4679. article

Using Nanowires to Extract Excitons from a Nanocrystal Solid

Dorn A.; Strasfeld D. B.; Harris D. K.; Han H.-S.; Bawendi M. G.

ACS Nano2011, 5, 9028–9033. article

Development of a Bioorthogonal and Highly Efficient Conjugation Method for Quantum Dots using Tetrazine-Norbornene Cycloaddition

Han H.-S.; Devaraj N. K.; Lee J.; Hilderbrand S. A.; Weissleder R.; Bawendi M. G.

J. Am. Chem. Soc. 2010, 132, 7838–7839. article

Surface-Structure-Regulated Cell-Membrane Penetration by Monolayer-Protected Nanoparticles

Verma A.; Uzun O.; Hu Y.; Hu Y.; Han H.-S.; Watson N.; Chen S.; Irvine D. J.; Stellacci F. 

 Nat. Mater. 2008, 7, 588–598. article

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