At Illinois

Pending Publications

  • Miller, R.; Lee, J.; Kim, Y.; Han, H.S.*; Kong, H.* In-drop thermal cycling of hydrophilic drug crystals to minimize variation in drug release and stem cell senescence.
  • Cowell T. C.; Han H.S.; “Robust double emulsion compartments for high-throughput nucleic acid detection by flow cytometry”, In Methods in Molecular Biology: Single-cell assays; Microfluidics, Genomics and Drug Discovery, coming 2023.

* Indicates corresponding author(s)


  1. Miller R.; Kim Y.; Park C. G.; Torres, C.; Kim, B.; Lee, J.; Flaherty, D.; Han H.S.; Kim Y. J.*; Kong, H.* “Extending the bioavailability of hydrophilic antioxidants for metal ion detoxification via recrystallization with polysaccharide dopamine”, ACS Appl. Mater. Interfaces, 2022, 14, 35, 39759–39774. article
  2. Martin J.; Lanning, R.; Chauhan, V.; Martin, M.; Mousa, A.; Kamoun, W.; Han H.S.; Lee, H.; Stylianopoulos T.; Bawendi M.; Duda D.; Brown, E.; Padera T.; Fukumura D.; Jain R. “Multiphoton phosphorescence quenching microscopy reveals kinetics of tumor oxygenation during anti-angiogenesis and angiotensin signaling inhibition, Clinical Cancer Research, 2022, 28, 14, 3076-3090. article
  3. Jing W.; Han H.-S.* “Droplet Microfluidics for High-Resolution Virology”, Anal. Chem. (invited Perspective), 2022, 94, 23, 8085–8100. article
  1. Cowell T.; Dobria A.; Han H.-S.* “Simplified, Shear Induced Generation of Double Emulsions for Robust Compartmentalization during Single Genome Analysis” Biorxiv 2021/469484. ACS Appl. Mater. Interfaces, 2022, 14, 18, 20528–20537. article
  1. Jing W.; Han H.-S.* “Inertial Self-Assembly Dynamics of Interacting Droplet Ensembles in Microfluidic Flows” arXiv2021;2104.04655. Analytical Chemistry, 2022, 94, 9, 3978-3986. article
  2. Park J.; Jayaraman, A. R.; Wang X.; Zhao J.; Han H.-S.* “Nanocrystal Precursor Incorporating Separated Reaction Mechanisms for Nucleation and Growth to Unleash the Potential of Heat-up Synthesis” ACS Nano, 2020, 14, 9, 11579-11593. article
  1. Park J.; Jayaraman, A. R.; Schrader, A. W.;  Hwang G.W.; Han H.-S.* “Controllable modulation of precursor reactivity using chemical additives for systematic synthesis of high-quality quantum dots” Nature Comm, 2020, 11, 5748. article (selected as Editor’s highlight, featured article in Materials Science and Chemistry)
  2. Cowell T. C.; Valera E.; Jankelow A; Park J.; Schrader A.; Ding R.; Berger J; Bashir R.; Han H.-S.* “Rapid, Multiplexed Electrical Detection of Biomolecules using Electrically Distinct Hydrogel Beads”, Lab Chip. 2020, 20, 2274-2283. article (selected as the inside front cover article)
Microfluidic Synthesis of Multiplexing Beads


  • Han H.-S. and Park J. “Precursor chemistry for quantum dot synthesis enabling temperature-independent modulation of reactivity” Provisionally submitted.
  • Han H.-S., Bashir R., Cowell T. and Valera E. “Electrically distinct hydrogel microparticles for multiplexed detection, quantification and barcoding” U.S.#20200391169. Dec. 17, 2020.

Prior Research


  • Han H.-S.; Cantalupo P. G.; Rotem A.; Cockrell S. K.; Carbonnaux M.; Pipas J. M.; Weitz D. A. “Whole-Genome Sequencing of a Single Viral Species from a Highly Heterogeneous Sample” Angew. Chem. Int. Ed2015, 54, 13985–13988. article
    * Above article was selected as a “Hot paper”.
  • Han H.-S.; Niemeyer E.; Huang Y.; Kamoun W. S.; Martin J. D.; Bhaumik J.; Chen Y.; Roberge S.; Cui J.; Martin M. R.; Fukumura D.; Jain R. K.; Bawendi M. G.; Duda D. G. “Quantum Dot/Antibody Conjugates for In vivo Cytometric Imaging in Mice” Proc. Natl. Acad. Sci. U.S.A. 2015, 112, 1350–1355. article
  • Chen O.; Zhao J; Chauhan V. P.; Cui J.; Wong C.; Harris D. K.; Wei H.; Han H.-S.; Fukumura D.; Jain R. K.; Bawendi M. G. “Compact High-Quality CdSe-CdS Core-Shell Nanocrystals with Narrow Emission Linewidths and Suppressed blinking” Nat. Mater. 2013, 12, 445–451. article
  • Manfrinato V. R.; Wanger D.D.; Strasfeld D. B.; Han H.-S.; Marsili F.; Arrieta J. P.;Mentzel T. S.; Bawendi M. G.; Berggren K. K. “Controlled Placement of Colloidal Quantum Dots in sub-15-nm Clusters” Nanotechnology. 2013, 24, 125302. article
  • Han H.-S.; Martin J.; Lee J.; Harris D. K.; Fukumura D.; Jain R. K.; Bawendi M. G. “Spatial Charge Configuration Regulates Nanoparticle Transport and Binding Behavior in vivo” Angew. Chem. Int. Ed. 2013, 52, 1414–1419. article
    * Above article was highlighted in Nat. Mater. 2013, 12, 91.
  • Wei H.; Insin N.; Lee J.; Han H.-S.; Cordero J. M.; Liu W.; Bawendi M. G. “Compact Zwitterion-Coated Iron Oxide Nanoparticles for Biological Applications” Nano Lett2012, 12, 22–25. article
  • Harris D. K.; Allen P. M.; Han H.-S.; Walker B. J.; Lee J.; Bawendi M. G. “Synthesis of Cadmium Arsenide Quantum Dots Luminescent in the Infrared”, J. Am. Chem. Soc. 2011, 133, 4676–4679. article
  • Dorn A.; Strasfeld D. B.; Harris D. K.; Han H.-S.; Bawendi M. G. “Using Nanowires to Extract Excitons from a Nanocrystal Solid” ACS Nano2011, 5, 9028–9033. article
  • Han H.-S.; Devaraj N. K.; Lee J.; Hilderbrand S. A.; Weissleder R.; Bawendi M. G. “Development of a Bioorthogonal and Highly Efficient Conjugation Method for Quantum Dots using Tetrazine-Norbornene Cycloaddition” J. Am. Chem. Soc. 2010, 132, 7838–7839. article
  • Verma A.; Uzun O.; Hu Y.; Hu Y.; Han H.-S.; Watson N.; Chen S.; Irvine D. J.; Stellacci F. “Surface-Structure-Regulated Cell-Membrane Penetration by Monolayer-Protected Nanoparticles” Nat. Mater. 2008, 7, 588–598. article


  • Han H.-S., Pipas, J.M. and Weitz D.A. “Systems and Methods for Sequencing Viruses” Provisionally submitted.
  • Han H.-S., Wei H., Insin N. and Bawendi M. G. “Compact Nanoparticles for Biological Applications” W.O. Patent #2013090601, Aug. 8, 2013/U.S. #20130184444, July 18, 2013.
  • Han -S., Devaraj N. K., Hilderbrand S. A., Weissleder R. and Bawendi M. G. “Compositions and Methods for Bioconjugation to Quantum Dots” W.O. Patent #2011112970, Jan. 19, 2012.
  • Han H.-S., Liu W. and Bawendi M. G.Ligands for Semiconductor Nanocrystals” W.O. Patent #2011119654, Publication date: Sep. 29, 2011/U.S. #20110236315, Sep. 29, 2011